Uridine CAS 58-96-8 Purines and Pteredines 1-D-Ribofuranosyluracil

Description:

Uridine is one of the key nucleotide that making RNA^[1-3]. It is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring[or more specifically, a ribofuranose] via a β-N1-glycosidic bond. It is one of the five standard nucleosides which make up nucleic acids[including both RNA and DNA] with the others four being adenosine, thymidine, cytidine and guanosine. The five nucleosides are commonly abbreviated to their one-letter codes U, A, T, C and G respectively. Thymidine is found in deoxyribonucleic acid[DNA] and not ribonucleic acid(RNA]. Conversely, uridine is found in RNA and not DNA^{[1, 3]}. The remaining three nucleosides can be found in both RNA and DNA. In RNA, they would be represented as A, C and G whereas in DNA they would be represented as dA, dC and dG^[1,3].

Basic Parameters:

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Uses:

Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond.

Uridine is a nucleoside; widely distributed in nature. Uridine is one of the four basic components of ribonucleic acid (RNA)

Biochem Actions:

Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine are implicated in insulin resistance.